The TLC series “My 600-Lb. Life” has introduced fans to memorable people as it highlights their struggles with weight loss and health. Since the start of the reality TV show in 2012, we have seen triumphs and failures, and, sadly, some participants have passed away, including these two stars in 2025.
Pauline Potter
Pauline Potter died in November, Us Weekly reports. She was 62. Her son, Dillion, shared the news on November 30, revealing his mother had been in a car accident earlier in the year, which had left her with lasting health issues. Her health had significantly declined from this incident.
Fans got to know Potter when she appeared on “My 600-Lb. Life” Season 3 in 2015. When she first appeared on the show a decade ago, she weighed 673.5 pounds and eventually lost 149 pounds on the episode, Us Weekly reports. In 2016, she “was named the heaviest living woman by Guinness World Records, which recorded her weight at 647.4 pounds,” the publication states.
Potter would lose significant amounts of weight four years later. In November 2020, she shared several photos on Facebook showing a much slimmer figure. Fans flooded social media with support for her weight loss journey.
Latonya Pottain
Latonya Pottain appeared on Season 11 in 2023. She died from “chronic congestive heart failure” at an inpatient medical rehabilitation facility on May 17, E! News reports. She was 40.
“She experienced a medical event and was transported to Christus Highland Hospital by emergency medical services, where she was later pronounced deceased at 22:29 hours on May 17, 2025,” authorities shared in a statement, E! News reports. Pottain had struggled significantly with her weight before her death, reaching out to the public for support in a GoFundMe fundraiser.
E! News shared a throwback video from Pottain’s time on the show on Facebook. Fans reacted to the news of her passing on the post.
Bariatric surgeon Dr. Younan Nowzaradan, who is part of the show and offers surgical intervention to those who qualify, revealed the goal and purpose of “My 600-Lb. Life” at the 2016 ObesityHelp National Conference.
“We continue to try to provide education for everyone. That’s the reason I started the television series, [which] was to make an impression on the medical community that they should take care of these patients,” Dr. Nowzaradan said. “Another reason important to me was to have a show that provided inspiration for people and for the medical community with my hope to change [biased] opinions about morbidly obese people.”
